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Brain Disorder Awards

2010-2012

Angélique Bordey, Ph.D., Yale University School of Medicine
Cognitive Deficits in Tuberous Sclerosis Complex

Rita Balice-Gordon, Ph.D.,, and Josep Dalmau, M.D, Ph.D., University of Pennsylvania School of Medicine
CCellular, Synaptic and Circuit Mechanisms of Autoimmune anti-Glutamate Receptor Disorders of Memory and Cognition

Michael DeWeese, Ph.D., University of California, Berkeley
Probing the Cortical Mechanisms of Working Memory

2009-2011

David Corey, Ph.D., Professor of Pharmacology and Biochemistry, University of Texas Southwestern Medical Center
Allele-Selective Inhibition of Mutant Huntingtin and Other Triplet Repeat Proteins

Robert H. Edwards, Ph.D., Professor of Neurology and Physiology, University of California, San Francisco, School of Medicine
The Regulation of Mitochondrial Morphology by Alpha-Synuclein

Mirjana Maletic-Savatic, M.D., Ph.D., Assistant Professor of Pediatrics, Section of Child Neurology, Baylor College of Medicine
Metabolomic Markers of Autism Spectrum Disorders

John A. Wemmie, M.D., Ph.D., Associate Professor, Psychiatry, Neurosurgery and Neuroscience; and Vincent A. Magnotta, Ph.D., Associate Professor of Radiology, University of Iowa
Dynamics of Brain pH in Psychiatric and Neurological Disease

X. William Yang, M.D., Ph.D., Associate Professor, Psychiatry and Biobehavioral Sciences, University of California, Los Angeles
Basal Ganglia Circuitry and Molecular Deficits in a Mouse Model of Tourette Syndrome

R. Suzanne Zukin, Ph.D., F.M. Kirby Professor in Neural Science and Neural Repair, Albert Einstein College of Medicine
Epigenetic Remodeling of Neuronal Genes in Global Ischemia

2008-2010

Ilya Bezprozvanny, Ph.D., University of Texas Southwestern Medical Center
Deranged calcium signaling and neurodegeneration in Alzheimer’s disease

Ming Guo, M.D., Ph.D., University of California, Los Angeles
Drosophila models of Parkinson disease

Maria Karayiorgou, M.D., Columbia University Medical Center
A genetic mouse model of schizophrenia implicates miRNA biogenesis in disease

Bingwei Lu, Ph.D., Stanford University School of Medicine
Understanding the molecular basis of synaptic dysfunction in Alzheimer’s disease

Colleen A. McClung, Ph.D., University of Texas Southwestern Medical Center
The role of CLOCK and CCK in the development and treatment of mania

Mark A. Tanouye, Ph.D., University of California, Berkeley
Neurological drug development using Drosophila seizure-suppressor mutants

2007-2009

Michael Bastiani, Ph.D., University of Utah
A genetic screen for genes influencing neuronal regeneration

Andrew Dillin, Ph.D., Salk Institute for Biological Studies
Age-associated neuroprotection by insulin/IGF-1 signaling: from worm to mouse

Andrew Lieberman, M.D., Ph.D., University of Michigan
Treatment of a polyglutamine neurodegenerative disease with synthetic bifunctional compounds that target misfolded proteins

Janice Naegele, Ph.D., Wesleyan University
Brain grafts of GABAergic neurons derived from embryonic stem cells for treating temporal lobe epilepsy

Lorna Role, Ph.D., State University of New York – Stony Brook
Neuregulin 1 regulation of nicotine-sensitive cortico-limbic circuits affected in schizophrenia

Charles Weitz, M.D., Ph.D., Harvard Medical School
Obesity, diabetes, and the arcuate nucleus circadian clock

2006-2008

C. Michael Crowder, M.D., Ph.D., Washington University School of Medicine
Identification of Genes Regulating Survival Following Hypoxic Insult in Caenorhabditis elegans

Guoping Feng, Ph.D., Duke University Medical Center
Understanding the Molecular and Cellular Basis of Obsessive-Compulsive Disorder Using a Novel Mouse Model

Jill Morris, Ph.D., Northwestern University and Children’s Memorial Research Center
The Role of DISC1 in Neuronal Migration

Jeffrey Noebels, M.D., Ph.D., and Richard Gibbs, Ph.D., Baylor College of Medicine
Profiling Ion Channel Genes in Autism

Alexander Schier, Ph.D., Harvard University
Genetic Analysis of Sleep Disorders in Zebrafish

2005-2007

Richard Andersen, Ph.D., California Institute of Technology
A Human Cortical Prosthetic to Assist Severely Paralyzed Patients

John Brigande, Ph.D., Oregon Health & Science University; and Stefan Heller, Ph.D., Harvard Medical School
Stem-Cell-Based Therapy for Hereditary Hearing Loss

William A. Catterall, Ph.D., University of Washington School of Medicine
Molecular Basis for Acquired Epilepsy in a Mouse Model

Sacha B. Nelson, M.D., Ph.D., and Gina G. Turrigiano, Ph.D., both of Brandeis University
A Physiological Genomics Approach to Understanding Rett Syndrome

Gregory A. Petsko, Ph.D., and Dagmar Ringe, Ph.D., both of Brandeis University
Genetic Analysis of Tau

Kai Zinn, Ph.D., California Institute of Technology
Prion Aggregates, Synaptic Translation, and Neurodegeneration

2004-2006

Seymour Benzer, Ph.D., California Institute of Technology
A Drosophila Model for the Functional Characterization of Apolipoprotein D and Its Role in Neurodegenerative Disease

Valina L. Dawson, Ph.D., Johns Hopkins University School of Medicine
Characterization of Novel Neuroprotective Molecules

Alan L. Goldin, M.D., Ph.D., University of California, Irvine
A Mouse Model of Human Epilepsy

Michael E. Greenberg, Ph.D., Children’s Hospital and Harvard Medical School
A Role for MeCP2 in Activity-dependent Regulation of Gene Expression and Rett Syndrome

Steven P. Hamilton, M.D., Ph.D., University of California, San Francisco
Canine Genetic Models of Human Anxiety Disorders

Irwin B. Levitan, Ph.D., University of Pennsylvania School of Medicine
Ion Channels and Sleep Disorders: Molecular Mechanisms and Novel Therapeutic Targets

2003-2005

Harvey Cantor, M.D., and Bruce Yankner, Ph.D., M.D., Harvard Medical School
Is Alzheimer’s an Autoimmune Disease?

Ronald L. Davis, Ph.D., Baylor College of Medicine
Genetic Risk Factors of Mood and Other Brain Disorders

Joseph A. Gogos, M.D., Ph.D., Columbia University, College of Physicians & Surgeons
Identification of the Underlying Disturbances in Schizophrenia Using Reliable Mouse Models of Susceptibility Genes

Paul H. Patterson, Ph.D., California Institute of Technology
A Mouse Viral Model for Study of the Pathogenesis and Prevention of Mental Illness

Scott A. Small, M.D., Columbia University
Alzheimer’s Disease Diagnosis and Drug Development Using Microscopic-Metabolic MRI

Vivien Yee, Ph.D., The Cleveland Clinic Foundation
Molecular Mechanisms in Spongiform Encephalopathies

Gary I. Yellen, Ph.D., Harvard Medical School
The Ketogenic Diet in Epilepsy Treatment: Learning the Mechanism

2002-2004

Maureen Condic, Ph.D., University of Utah School of Medicine
Contributions of Integrins to Adult Regenerative Failure

Fen-Biao Gao, Ph.D., University of California, San Francisco
Genetic Dissection of Fragile X Mental Retardation in Drosophila.

Kimberly Huber, Ph.D., University of Texas Southwestern Medical School
Mechanisms of Synaptic Plasticity in a Mouse Model of Retardation

Pat Levitt, Ph.D., University of Pittsburgh (he joins Vanderbilt University in June 2002)
Molecular Strategies toward Understanding Schizophrenia as a Disease of the Synapse

Emmanuel Mignot, M.D., Ph.D., Stanford University Sleep Research Center
Genetic Analysis of the Narcolepsy Pathway in Humans, Mice, and Zebrafish

Christopher Walsh, M.D., Ph.D., Harvard Medical School and Beth Israel Deaconess Medical Center
Genetic Disorders of Human Cerebral Cortical Development

2002-2004

Mel Feany, M.D., Ph.D., Harvard Medical School and Brigham and Women’s Hospital
Genetic Analysis of Alzheimer’s Disease in Drosophila

Oliver Hobert, Ph.D., Columbia University College of Physicians and Surgeons
Genetic Analysis of Kallmann’s Syndrome

Steven McKnight, Ph.D., University of Texas Southwestern Medical Center
Genetic Studies of Factors Controlling Rhythmic Behaviors in Humans and Mice

Margaret Pericak-Vance, Ph.D., and Jeffery Vance, M.D., Ph.D., Duke University Medical Center
Studies of Mitochondrial Haplogroups in Alzheimer Disease Families

Stephen Strittmatter, M.D., Ph.D., Yale University School of Medicine
Nogo Regulation of Axonal Regeneration and Plasticity